免疫因子联合疗法治疗

自身免疫性甲状腺疾病116例患者临床分析

A clinical analysis of treating116 cases of autoimmune thyroid disease by the immune factors combinationtherapy

李继华  曹淑芝

(北京丰台广济医院， 北京，100071)

中图分类号：R581      文献标识码：A    文章编号：1674-7860（2015）27-0040-03    证型：GIA

【摘  要】目的：观察运用免疫因子联合疗法治疗免疫性甲状腺疾病的临床疗效。方法：严格按照纳入标准将116例自身免疫性甲状腺疾病患者随机分2组，治疗组58例，对照组58例。采用免疫因子联合疗法治疗，采用常规抗甲状腺药物治疗。两组疗程均为3个月。观察患者治疗前后临床症状、体征和实验室化验、检查指标变化。结果：①两组患者治疗后有效率分别是98.3%和53.4%，临床治愈率分别是94.8%和43.1%，治疗组明显优于对照组，且差异性有统计学意义(P＜0.05)。②免疫因子联合疗法治疗后甲状腺抗体下降(P＜0.05)③免疫因子联合疗法治疗后可改善和消除免疫性甲状腺疾病各种临床症状、体征，治疗组优于对照组。结论：两组治疗方法对免疫性甲状腺疾病都有一定的改善作用，但治疗组总有效率和治愈率明显优于对照组。说明免疫因子联合疗法治疗免疫性甲状腺疾病疗效更佳。

【关键词】免疫因子联合疗法；免疫甲状腺疾病；瘿病；中医治疗甲状腺疾病

【Abstract】Objective:To investigate the combination therapy of immune factors for autoimmune thyroiddisease. Methods: 116 patients with autoimmune thyroid disease were randomlydivided into two groups, 58 cases for each. The combined therapy was given tothe treatment group, and the conventional antithyroid treatment was given tocontrol group. Clinical symptoms, signs and laboratory tests before and aftertreatment were recorded. Results:①Aftertreatment the efficiency were 98.3% and 53.4%,clinical efficacy were 94.8% and43.1% in the treatment group than the control group, and the difference wasstatistically significant (P＜0.05).② with immunefactors combination therapy, thyroid antibody decreased (P＜0.05).③immune factorsin combination therapy can improve and eliminate all kinds of clinical symptoms,signs in autoimmune thyroid disease, more in the treatment group than thecontrol group. Conclusion: Immune factors combination therapy for autoimmunethyroid disease show better effect.

【Keywords】Combinedimmune factor therapy; Immune thyroid diseases; Ying disease; TCM treatment forthyroid disease

doi:10.3969/j.issn.1674-7860.2015.27.018

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