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原发性肝癌通过血清甲胎蛋白和
高尔基体蛋白73检测的效果分析
Diagnosing PHC through detection of serumAFP and GP73
陆枝红 吴自宁
(北京首都国际机场医院,北京,100621)
中图分类号:R735.7 文献标识码:A 文章编号:1674-7860(2015)27-0123-03 证型:AGD
【摘 要】目的:分析原发性肝癌通过血清甲胎蛋白和高尔基体蛋白73检测的情况。方法:研究我院在2014年6月—2015年6月接诊的40例原发性肝癌(PHC)患者和40例单纯性肝癌患者,以及40例健康群体做对照组,对比三组患者在甲胎蛋白(AFP)和高尔基体蛋白73(GP73)上的检验结果差异。结果:PHC患者和单纯性肝癌者的AFP和GP73水平均高于健康组;其检测的敏感性上,GP73阳性率为72.5%,AFP阳性率为57.5%,两种方式联合情况下的阳性率为87.5%。结论:在原发性肝癌诊断中,AFP和GP73可以作为诊断的标志物,采用联合检验的方式可以提升检测的敏感性。
【关键词】原发性肝癌;甲胎蛋白;高尔基体蛋白73
【Abstract】Objective:To analyze PHC by detecting serumAFP and GP73. Methods: 40 cases of PHC and 40 cases of simple liver cancer, and40 healthy as control groups, recoded the three groups of the AFP and GP73 testresults. Results: in PHC and simple liver cancer patients, AFP and GP73 levelswere higher than the healthy group; For its detection sensitivity, GP73 Positiverate was 72.5%, AFP Positive rate was 57.5%, the Positive rate in two ways was 87.5%.Conclusion:PHC diagnosis, AFP and GP73 can be used as diagnostic markers wit a joint testof ways to enhance the sensitivity of detection.
【Keywords】PHC; AFP; GP73
doi:10.3969/j.issn.1674-7860.2015.27.060