氯沙坦联合氨氯地平治疗清晨高血压的疗效观察

Losartan and Amlodipine Treatment Efficacy of Morning Hypertension

金秀红

（密云县鼓楼社区卫生服务中心，北京，101500）

中图分类号：R54    文献标识码：A   文章编号：1674-7860(2015)21-0041-02    证型：BDG

【摘 要】目的：氯沙坦联合氨氯地平治疗清晨高血压的临床疗效和安全性。方法：选取60例清晨高血压的患者，随机分成两组，A组清晨口服氯沙坦50 mg，睡前口服氨氯地平5 mg；B组清晨口服氯沙坦50 mg。观察服药前及服药后8周清晨血压的变化，比较8周后两组清晨血压下降程度。结果：治疗后两组清晨收缩压、舒张压较治疗前明显下降，差异有统计学意义（P<0.05）；A组降压幅度大于B组（P<0.01）。结论：氯沙坦联合氨氯地平能有效控制清晨高血压。

【关键词】氯沙坦；氨氯地平；清晨高血压

【Abstract】Objective:Losartan and Amlodipine treatment Morning Hypertension clinical efficacy and safety.Methods: 60 patients with Morning Hypertension were randomly divided into two groups, A group of morning oral losartan 50 mg, orally at bedtime amlodipine 5 mg;group B morning oral losartan 50 mg.after 8 weeks observed changes before taking blood pressure medication and the two groups compare the extent of morning blood pressure after 8 weeks. Results: After treatment, Morning Systolic Blood Pressure,Diastolic Blood Pressure Decreased significantly compared with before treatment, the difference was statistically significant (P<0.05);A group of blood pressure reduction than that in group B (P<0.01). Conclusion: Losartan and amlodipine can effectively control hypertension in morning.

【Keywords】Losartan; Amlodipine; Morning Hypertension

doi:10.3969/j.issn.1674-7860.2015.21.021

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